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DrTim's Aquatics Reef One & Only Nitrifying Bacteria – For Reef, Nano and Seahorse Aquaria, New Fish Tanks, Aquariums, Disease Treatment – H20 Pure Fish Tank Cleaner – Removes Toxins – 4 Oz. (401)

4.5 4.5 out of 5 stars 1,698 ratings

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List Price: $32.39

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4 oz
One & Only REEF-PURE
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Purchase options and add-ons

Brand DrTim's Aquatics
Liquid Volume 4 Fluid Ounces
Item Weight 4 Ounces
Item Form Liquid
Target Species Fish

About this item

  • THE BEST WAY TO SANITIZE A REEF, NANO AND SEAHORSE AQUARIUM: One & Only from DrTim’s Aquatics quickly converts waste in aquariums and fish tanks to a non-toxic form. Utilize this powerful solution when setting up new fish tanks, while cleaning filters or adding new fish or after a water change.
  • REMOVES HARMFUL TOXINS FROM REEF, NANO AND SEAHORSE FISH TANKS: Even with regular water changes and maintenance, aquariums and fish tanks produces bad bacteria and it can take up to 30 days to eliminate waste. Not with Reef, Nano and Seahorse One & Only because this solution instantly creates a bio filter to remove nitrite and toxic ammonia naturally.
  • 100% NATURAL, ECO-FRIENDLY FISH TANK CLEANER: There’s no need to wait when treating your new Reef, Nano and Seahorse aquarium or fish tank with One & Only. This fish tank cleaner eliminates new tank syndrome and does not include sulfur or other offensive odors.
  • AQUARIUM SUPPLIES YOU NEED: Offer your pet fish and corals an environment in which they can thrive with this One & Only for Reef, Nano and Seahorse fish tanks and aquariums. One & Only is available in quantities that include 2, 4, 8, 16, 32, 64 and 128 ounces.
  • HIGH-QUALITY AQUARIUM PRODUCTS: DrTim’s Aquatics offers an expansive line of aquarium products used by professionals and residential customers. Based on years of experience in marine biology, DrTim’s Aquatics’ products utilize his vast knowledge and are backed by scientific evidence and innovative research.
  • age range description: All Life Stages

Customer ratings by feature

Easy to use
3.6 3.6
Value for money
3.6 3.6
Stability
3.5 3.5
Accuracy
2.7 2.7

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Product Description

coral reef products

about drtim's

DrTim's Aquatics makes 100% natural products for freshwater, saltwater, and reef aquariums and Koi ponds and water gardens like One & Only Live Nitrifying Bacteria, AquaCleanse water de-toxifiers, First Defense stress relief, Clear-Up water clarifier, Re-Fresh surface cleaner, Eco-Balance Probiotics, Waste-Away sludge buster.. We offer a variety of products to successfully start up and maintain fish tanks and aquariums of all types and sizes.

DrTim’s Aquatics Reef Safe One & Only Live Nitrifying Bacteria

Live Nitrifying Bacteria Eliminates New Tank Syndrome & Eliminates Toxic Ammonia and Nitrite

DrTim’s Aquatics One & Only Live Nitrifying Bacteria prevents New Tank Syndrome by instantly working to establish a bio filter in newly set-up fish tanks and aquariums. Our highly effective water treatment solution can be used to convert fish waste to a non-toxic form and is safe to add to tanks with fish. For best results use when setting up a new tank, after a water change, cleaning your filter, when adding new fish, and after a treatment.

  • Eliminates New Tank Syndrome
  • Can be used with fish in the tank
  • Naturally removes toxic ammonia & nitrite
  • Instantly creates a bio filter
  • No sulfur or other offensive odors
freshwater fish

For enhanced results, we recommend using Dr. Tim’s Ammonium Chloride Solution for Fishless Cycling and DrTim's One & Only Nitrifying Bacteria in your new tank. Using these products together offers a stress free method for cycling a new aquarium when fish or coral are not present. Our easy to follow process will instantly create a bio filter that eliminates New Tank Syndrome by naturally removing toxic ammonia and nitrite. .

DrTim’s Prescription For Fishless Cycling a New Aquarium

1 - Bottle of DrTim’s One & Only Sized to Your Tank

1- Bottle of DrTim’s Ammonium Chloride

1- Bottle of DrTim’s Aquatics First Defense

Test Kits for Ammonia, Nitrite and pH

benefits of one and only

aquarium drops

fresh water fish tank

Reef Safe One & Only Live Nitrifying Bacteria converts fish waste into a non-toxic form and removes ammonia and nitrite. By doing so, this instantly works to prevent New Tank Syndrome, which occurs when the water contains high level of ammonia and nitrite and there are not enough beneficial bacteria to process it, by establishing a biological filter in newly set-up fish tanks and aquariums.

One & Only Live Nitrifying Bacteria is reef safe and instantly establishes a biological filter with 100% natural living nitrifiers in newly set-up fish tanks and aquariums so that your fish don't experience New Tank Syndrome. Our effective solution does this by containing species of ammonia- and nitrite-oxidizing bacteria that prefer to live in the fish tank environment and contains no sulfur or other offensive odors.

Use when setting up a new aquarium, adding new fish to the tank, after water changes, when cleaning the filter, and treatment to quickly establish a natural biological filter. We recommend using the entire contents at one time with a minimum dose of 10mL (2 capfuls) per 10 gal. Our solution cannot be overdosed and can be used immediately with new fish. Be sure to turn-off UV and remove filter socks for at least 48 hours.

best aquarium solutions
Ammonium Chloride Aquarium Treatment aqua cleanse first defense tank clear up tank refresh eco balance fish tank
Ammonium Chloride AquaCleanse Tapwater Conditioner First Defense Stress Relief Clear-Up Natural Water Clarifier Re-Fresh Natural Surface Cleaner Eco-Balance Natural Probiotic
Customer Reviews
4.7 out of 5 stars
3,102
4.5 out of 5 stars
1,698
4.5 out of 5 stars
1,698
4.5 out of 5 stars
1,698
4.5 out of 5 stars
1,698
Price $7.99 $15.90 $15.94 $14.99
Product Size (oz.) 2, 4, & 8 2, 4, 8, 16, 32, 64, & 128 2, 4, 8, 16, 32, 64, & 128 2, 4, 8, 16, 32, 64, & 128 2, 4, 8, 16, 32, 64, & 128 2, 4, 8, 16, 32, 64, & 128
Amount of Water Treated (gal. 100, 200, & 400 120, 240, 480, 960, 1920, 3840, & 7680 120, 240, 480, 960, 1920, 3840, & 7680 120, 240, 480, 960, 1920, 3840, & 7680 120, 240, 480, 960, 1920, 3840, & 7680 60, 120, 240, 480, 960, 1920, 3840
Benefits Chlorine-free method for sanitizing new aquaria or when cycling water when fish or coral are not present Eliminates common chemicals in tap water & removes chlorine, chloramines, and ammonia Helps fish adapt to new environments with a mixture of vitamins and immunostimulants Clears up cloudy, white water without chemicals Revitalizes old, green/brown water & keeps water odor free Maintains a balanced, healthy aquarium environment, blocks out unfriendly bacteria, & promotes optimal water quality
Usage ​​When setting up a new tank, use with One & Only Live Nitrifying Bacteria to create a bio filter and remove harmful toxins. Before setting up a new tank When doing partial water changes, during treatments and when fish are showing signs of stress When water starts to become cloudy/white When water starts to become brown/green Use on a weekly basis to restore and maintain a clean, balanced, healthy aquarium

From the brand

Product information

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DrTim's Aquatics Reef One & Only Nitrifying Bacteria – For Reef, Nano and Seahorse Aquaria, New Fish Tanks, Aquariums, Disease Treatment – H20 Pure Fish Tank Cleaner – Removes Toxins – 4 Oz. (401)

DrTim's Aquatics Reef One & Only Nitrifying Bacteria – For Reef, Nano and Seahorse Aquaria, New Fish Tanks, Aquariums, Disease Treatment – H20 Pure Fish Tank Cleaner – Removes Toxins – 4 Oz. (401)


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Product details

  • Product Dimensions ‏ : ‎ 2.5 x 1.25 x 4.75 inches; 4 ounces
  • Item model number ‏ : ‎ 401
  • Date First Available ‏ : ‎ November 21, 2008
  • Manufacturer ‏ : ‎ DrTim's Aquatics, LLC
  • ASIN ‏ : ‎ B001LUOB6W
  • Customer Reviews:
    4.5 4.5 out of 5 stars 1,698 ratings

Important information

Ingredients

100-Percent natural aquarium nitrifying bacteria

Directions

Shake well before using. It is best to use the entire contents at one time. Cannot be overdosed. Add directly to the aquaria. Make sure any UV and ozone systems are off for 48 hours after adding.

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DrTim's Aquatics Reef One & Only Nitrifying Bacteria – For Reef, Nano and Seahorse Aquaria, New Fish Tanks, Aquariums, Disease Treatment – H20 Pure Fish Tank Cleaner – Removes Toxins – 4 Oz. (401)
DrTim's Aquatics Reef One & Only Nitrifying Bacteria – For Reef, Nano and Seahorse Aquaria, New Fish Tanks, Aquariums, Disease Treatment – H20 Pure Fish Tank Cleaner – Removes Toxins – 4 Oz. (401)
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DrTim's Aquatics Reef Waste-Away 4 oz
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Price-32% $22.10
List:$32.39
$14.75$25.99$6.26-8% $10.99
Typical:$11.98
$11.19
Delivery
Get it as soon as Monday, May 27
Get it as soon as Monday, May 27
Get it as soon as Tuesday, May 28
Get it as soon as Tuesday, May 28
Get it as soon as Monday, May 27
Get it as soon as Wednesday, May 29
Customer Ratings
Easy to use
3.6
4.4
3.9
4.3
4.3
4.6
Value for money
3.6
4.0
3.5
4.2
4.2
3.7
Stability
3.5
4.0
3.7
4.2
4.2
4.1
Accuracy
2.7
4.5
4.5
2.7
Sold By
Got Pets
Amazon.com
Amazon.com
FREE 3 DAY ARRIVAL SHIPPING
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ZQUARED
target species
Fish
Fish
Fish
Fish
Fish
Seahorse, Fish
liquid volume
4 fluid ounces
250 milliliters
250 milliliters
2 fluid ounces
8 fluid ounces
120 milliliters
form
Liquid
Liquid
Liquid
Ammonium
Ammonium
Liquid
weight
0.3 pounds
0.6 pounds
10.41 ounces
2 ounces
0.6 pounds
0.1 pounds

Customer reviews

4.5 out of 5 stars
4.5 out of 5
1,698 global ratings

Customers say

Customers are positive about the quality of the aquarium pond water treatment. They say it's a great product to add good bacteria to your tank, and that it'll keep your tank clean. However, some customers disagree on performance.

AI-generated from the text of customer reviews

75 customers mention61 positive14 negative

Customers like the quality of the aquarium pond water treatment. They mention it's a great product to add good bacteria to your tanks and helps keep them clean. The extra bacteria is food for your corals and seems to help the corals.

"...Everyone who has a tank should keep this on hand at all times. It's amazing." Read more

"...It arrived on time and in excellent condition" Read more

"It helps clean up sludge and can help your skimmer pull excess nutrients and build-up out of a system...." Read more

"...large aquarium of 300 gallons and this is probably one of the most helpful products I have ever had to disintegrate the byproducts left by my huge..." Read more

73 customers mention50 positive23 negative

Customers are mixed about the performance of the aquarium pond water treatment. Some mention that it works pretty good, does what it's claimed to do, and works great for fishless cycling. It also helps keep your filters working better, and it works right away on the algae that they had on their coral frags. However, others say that it just didn't work as advertised, did not solve any of their issues, and these fast cycling elixirs didn''t.

"This stuff is absolutely amazing. I use it when I set up a new tank, or even sometimes after a water change just to beef up the beneficial bacteria...." Read more

"Works great for fishless cycling" Read more

"...Product did not perform as advertised, but was still able to get some Nitrate at the end...." Read more

"...After acclimation to tank temp and salinity these animals have done extremely well...." Read more

Fishless cycle with Dr Tim's & ammonium nitrate works!!!
5 Stars
Fishless cycle with Dr Tim's & ammonium nitrate works!!!
Followed the directions to a T and it worked! 💪Set up: Recife eco 40 - Carib Sea dry rock and live sand. Ai 16hd, Nero 3 wave maker, and Axis 40 controlable pump. Added after boi cycle 2 clowns, 2 cleaner shrimp. Added a week ago after turning on the lights: a small colony of birdsnest and a plating montipora.So far elementary parameters have stabilized. I've also added algea barn galaxy-pods to help win on any nuisance algea buildup.Will update this post as time goes on.
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Top reviews from the United States

Reviewed in the United States on May 7, 2024
Size: 8 ozStyle: Waste-Away REEF-PUREVerified Purchase
Don't buy anything else! Seriously!
Reviewed in the United States on April 17, 2024
Size: 8 ozStyle: One & Only REEF-PUREVerified Purchase
Cycles tank quickly if directions are followed
Reviewed in the United States on June 2, 2023
Size: 2 ozStyle: One & Only REEF-PUREVerified Purchase
This stuff is absolutely amazing. I use it when I set up a new tank, or even sometimes after a water change just to beef up the beneficial bacteria. You can add fish immediately, no more waiting weeks for a tank to cycle. If you worried about over stocking, and about to add another fish, just add another bottle. My tank has never looked so clean and it totally skipped the "ugly stage" that most tanks go through. I always keep an extra bottle on hand just for incase moments. Once I needed to set up a hospital tank for a sick fish, and I didnt have time to wait for the tank to cycle, i just added this and then was good to go. Everyone who has a tank should keep this on hand at all times. It's amazing.
2 people found this helpful
Report
Reviewed in the United States on April 5, 2024
Size: 8 ozStyle: One & Only REEF-PUREVerified Purchase
I used a bunch of different products for aquarium startup to create the bacteria. Bunch of fish loss over $400 in fish loss. No other product ever really worked. I put this product in within two weeks. I had a fully running fish tank with multiple different fish this is the best product on the market when it comes to starting a fish tank.
One person found this helpful
Report
Reviewed in the United States on April 17, 2024
Size: 4 ozStyle: First Defense REEF-PUREVerified Purchase
Seems to be working. Delivery was weird. Why did I get the bacteria 2 days before the Ammonium Clouride? Better than bacteria sitting in a warehouse in Arizona or someplace hot, but... Getting the readings that I was hoping for.
Reviewed in the United States on April 16, 2024
Size: 8 ozStyle: One & Only REEF-PUREVerified Purchase
The media could not be loaded.
 Followed the directions to a T and it worked! 💪
Set up: Recife eco 40 - Carib Sea dry rock and live sand. Ai 16hd, Nero 3 wave maker, and Axis 40 controlable pump. Added after boi cycle 2 clowns, 2 cleaner shrimp. Added a week ago after turning on the lights: a small colony of birdsnest and a plating montipora.
So far elementary parameters have stabilized. I've also added algea barn galaxy-pods to help win on any nuisance algea buildup.
Will update this post as time goes on.
Customer image
5.0 out of 5 stars Fishless cycle with Dr Tim's & ammonium nitrate works!!!
Reviewed in the United States on April 16, 2024
Followed the directions to a T and it worked! 💪
Set up: Recife eco 40 - Carib Sea dry rock and live sand. Ai 16hd, Nero 3 wave maker, and Axis 40 controlable pump. Added after boi cycle 2 clowns, 2 cleaner shrimp. Added a week ago after turning on the lights: a small colony of birdsnest and a plating montipora.
So far elementary parameters have stabilized. I've also added algea barn galaxy-pods to help win on any nuisance algea buildup.
Will update this post as time goes on.
Images in this review
Customer image
Customer image
Reviewed in the United States on December 3, 2015
Size: 4 ozStyle: One & Only REEF-PUREVerified Purchase
Honestly I have heard good things about this solution, but my experience was not congruent with others' experiences. I bought this bottle to treat my 65 gallon reef setup (full of live rock, over 70 pounds), and enacted the fish-less cycling procedure with Dr. Tim's own ammonia bottle. Now I do have a 20 gallon sump as well, so when ammonia would not read down the first three days (and no nitrite reading), I thought maybe I didn't have enough Dr. Tim's for my system. So I went to my local LFS and bought a bottle for 30 gallons and added this. Still, no help. But, I did put Seachem Prime into my tank originally since I had rinsed my dry rock with tap water outside and wanted to get rid of the metals (All the rest of my water was RO/DI). I believe the prime converted the ammonia that I had originally inserted into ammonium, thus giving me incorrect readings on my API Ammonia tests since those tests measure a combined Ammonia and Ammonium (Ammonium is not toxic to fish, at least in low levels). So after contacted Dr. Tim's support, I kept going and trying to see what would happen. I didn't put much trust in my ammonia readings, but my nitrite readings were very low (either 0 or .25-.5 PPM) for more than a week, and trace nitrate. Well, I decided to try to add a damsel at this point because according to Dr. Tim's, I should be cycled at this point (as their product actually suggests you add fish immediately, but I didn't want to kill the fish or put it through stress). Long story short, it's been over 2 weeks, I have 5PPM nitrite readings, 5PPM nitrate readings, and ammonia readings that I cannot trust. All this with one fish in a 85+ gallon setup and minimal feeding. This does not sound like a cycled tank, and clearly their nitrifying bacteria is not doing its job (but clearly the ammonia converting bacteria is). They also do not have a money back guarantee (they literally told me that it was not a water quality issue, which makes no sense), so buyer beware since this product is not really that cheap. I hope I am an exception though since I never write one star reviews, but I just wanted to save some people from unnecessary grief (if your experiences mirror mine). I will be cycling my tank the normal way now with a dead table shrimp and wait it out.
3 people found this helpful
Report
Reviewed in the United States on January 13, 2024
Size: 16 ozStyle: Waste-Away REEF-PUREVerified Purchase
Product seemed to be helpful in the maintenance of my reef tank. It arrived on time and in excellent condition

Top reviews from other countries

Gamolmat Mokharat
5.0 out of 5 stars Good
Reviewed in Canada on December 3, 2023
Size: 8 ozStyle: One & Only REEF-PUREVerified Purchase
Good
Arkam
1.0 out of 5 stars Go buy another
Reviewed in Canada on October 18, 2023
Size: 16 ozStyle: One & Only REEF-PUREVerified Purchase
Back to microbacter. Thanks for getting two of my designer clownfish killed. Don’t play yourself this is overpriced too all superior brands are at max half the price. What a joke.
Amazon Customer
5.0 out of 5 stars Works!
Reviewed in Canada on June 26, 2023
Size: 4 ozStyle: One & Only REEF-PUREVerified Purchase
I used this product plus also seeded with some small pieces of live rock. Tank cycled within two weeks. Delivery was quick and it was well packaged.
Barks
1.0 out of 5 stars Did nothing for my cyano
Reviewed in the United Kingdom on May 2, 2024
Size: 8 ozStyle: Re-Fresh REEF-PUREVerified Purchase
Used refresh and waste away as instructed and it did nothing for my cyano
Overlord1944
5.0 out of 5 stars Did the job in my new tank
Reviewed in the United Kingdom on September 26, 2023
Size: 8 ozStyle: One & Only REEF-PUREVerified Purchase
I bought this to cycle a new 255 litre reef tank. The instructions were very clear and there are a couple of very useful videos on line. I followed the instructions to the letter in terms of dosing and testing and the cycle happened just as should, going through the various stages. Personally I much prefer to use something like this rather than use a live fish which would likely be stressed by the poor water quality during the cycle. One concern I did have was that if you followed the instructions fully it states that the tank would be ready for fish after 9 days. This certainly wasn’t the case and it wasn’t until day 15 the the nitrate levels had fallen to zero making the tank fully cycled. I would suggest not following the 9 day suggestion but relying on the results from ammonia, nitrite and nitrate tests. However I was still happy with a 15 day cycle so would use this again if I ever start a new tank.